Overview

  • Product name
    Anti-PDE3B antibody [SMCP3B]
    See all PDE3B primary antibodies
  • Description
    Rat monoclonal [SMCP3B] to PDE3B
  • Host species
    Rat
  • Specificity
    ab95814 is specific to PDE3B. It does not react with PDE3A.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Does not react with: Human
  • Immunogen

    Recombinant fragment, corresponding to C terminal amino acids 643-1100 of Mouse PDE3B expressed in E. coli.

  • Positive control
    • Mouse heart lysate; Mouse lymph node cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab95814 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 124 kDa.

Target

  • Function
    Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism.
  • Tissue specificity
    Abundant in adipose tissues.
  • Sequence similarities
    Belongs to the cyclic nucleotide phosphodiesterase family. PDE3 subfamily.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5''-cyclic phosphodiesterase B antibody
    • Adipocyte cAMP phosphodiesterase cGMP inhibited antibody
    • AI847709 antibody
    • cAMP Phosphodiesterase, adipocyte, cGMP-inhibited antibody
    • CGI-PDE B antibody
    • CGIP1 antibody
    • CGIPDE B antibody
    • CGIPDE1 antibody
    • cGMP inhibited 3 5 cyclic phosphodiesterase B antibody
    • CGMP inhibited cAMP phophodiesterase antibody
    • cGMP-inhibited 3'' antibody
    • Cyclic GMP inhibited phosphodiesterase B antibody
    • Cyclic GMP-inhibited phosphodiesterase B antibody
    • Cyclic nucleotide phosphodiesterase antibody
    • HcGIP1 antibody
    • HcGIP1, rat, homolog of antibody
    • Pde3b antibody
    • PDE3B_HUMAN antibody
    • Phosphodiesterase 3B antibody
    • Phosphodiesterase 3B cGMP inhibited antibody
    see all

Images

  • All lanes : Anti-PDE3B antibody [SMCP3B] (ab95814) at 2 µg/ml

    Lane 1 : Mouse heart cell lysate
    Lane 2 : Mouse lymph node cell lysate

    Secondary
    All lanes : Anti-Rat IgG HRP

    Performed under reducing conditions.

    Predicted band size: 124 kDa



    Run on a 3-8% Tris-Acetate gel.

References

This product has been referenced in:
  • Vang AG  et al. Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac. Biochem J 456:463-73 (2013). Read more (PubMed: 24007532) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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