Overview

  • Product name
    Anti-PDE4A4 antibody
  • Description
    Rabbit polyclonal to PDE4A4
  • Specificity
    Does not cross react with PDE4A1, A8 or A5 proteins and PDE4B, PDE4C and PDE4D or with other PDE family members.
  • Tested applications
    Suitable for: IP, WB, ICCmore details
  • Species reactivity
    Reacts with: Mouse, Rabbit, Human
  • Immunogen

    N-terminus PDE4A4 synthetic cyclic peptide.

  • Positive control
    • Tested with U937 cells, human SHSY-5Y and Jurkat cell extracts.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.01% Thimerosal (merthiolate)
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab14609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at an assay dependent dilution.
WB 1/500. Detects a band of approximately 125 kDa.
ICC Use at an assay dependent dilution.

Target

  • Relevance
    The PDE4 family of cAMP-specific phosphodiesterases represents an important therapeutic and pharmacological target for their anti-inflammatory and anti-depressant effects. Four distinct genes (PDE4A, PDE4B, PDE4C and PDE4D), encode large family of PDE4 isoforms. Almost all of these isoforms have a common core made up of central catalytic domain and C-terminal tail.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • DPDE2 antibody
    • PDE4A antibody
    • Phosphodiesterase 4 antibody
    • Phosphodiesterase 4A antibody

References

ab14609 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab14609.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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