For the best experience on the Abcam website please upgrade to a modern browser such as
Product name Anti-PDE4B antibody See all PDE4B primary antibodies
Goat polyclonal to PDE4B
Specificity This antibody is expected to recognise all reported isoforms (NP_002591.2, NP_001032418.1, NP_001032416.1 and NP_001032417.1).
Tested applications Suitable for:
WB more details
Predicted to work with:
Rat, Human, Chimpanzee, Macaque Monkey
DIDIATEDKSPVDT , from the C-terminal region of Human PDE4B
Mouse brain lysate. Lysate prepared from transfected HEK293 cells transiently expressing Human PDE4B.
Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3
Concentration information loading...
Purity Immunogen affinity purified
Purification notes Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 85 kDa (predicted molecular weight: 83 kDa).
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents.
Tissue specificity Expressed in brain, heart, lung and skeletal muscle.
Pathway Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
Sequence similarities Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
Information by UniProt
5''-cyclic phosphodiesterase 4B antibody
cAMP-specific 3'' antibody
cAMP-specific 3',5'-cyclic phosphodiesterase 4B antibody
Anti-PDE4B antibody images
References for Anti-PDE4B antibody (ab77272)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"