Anti-PDE4C antibody (ab14608)

Overview

  • Product nameAnti-PDE4C antibody
    See all PDE4C primary antibodies
  • Description
    Rabbit polyclonal to PDE4C
  • SpecificityThis antibody detects 3 isoforms of PDE4C subclasses (PDE4C1, PDE4C2 and PDE4C3).
  • Tested applicationsSuitable for: IP, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins).

  • Positive control
    • recombinant protein PDE4C1/2

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: 0.02% Thimerosal / Merthiolate
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Associated products

Applications

Our Abpromise guarantee covers the use of ab14608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP 1/20.
WB 1/500. Predicted molecular weight: 80 kDa.Can be blocked with PDE4C peptide (ab169990).

Target

  • FunctionHydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
  • Tissue specificityExpressed in various tissues but not in cells of the immune system.
  • PathwayPurine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1.
  • Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5''-cyclic phosphodiesterase 4C antibody
    • cAMP specific 3' 5' cyclic phosphodiesterase 4C antibody
    • cAMP-specific 3'' antibody
    • DPDE 1 antibody
    • DPDE1 antibody
    • MGC126222 antibody
    • PDE 21 antibody
    • PDE 4C antibody
    • PDE21 antibody
    • Pde4c antibody
    • PDE4C_HUMAN antibody
    • Phosphodiesterase 4C antibody
    • Phosphodiesterase 4C cAMP specific antibody
    • Phosphodiesterase 4C, cAMP specific (phosphodiesterase E1 dunce homolog, Drosophila) antibody
    • Phosphodiesterase E1 dunce homolog antibody
    • Phosphodiesterase E1 dunce homolog Drosophila antibody
    • Phosphodiesterase type 4C antibody
    see all

References for Anti-PDE4C antibody (ab14608)

ab14608 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Rat Cell lysate - whole cell (Astrocytes)
Loading amount 40 µg
Specification Astrocytes
Gel Running Conditions Reduced Denaturing (12)
Blocking step BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
Username

Abcam user community

Verified customer

Submitted Jan 24 2013

Thank you for your enquiry. 1) PDE4A antibody (ab14607) does not cross react to any known PDE4 subtype except all the PDE4A subtype variants including PDE4A1, A5, Ax, A8, it has little or no reactivity towards PDE4A10 and PDE4A11. We have tested fo...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"