Overview

  • Product nameAnti-PDE4DIP antibody
    See all PDE4DIP primary antibodies
  • Description
    Rabbit polyclonal to PDE4DIP
  • Tested applicationsSuitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence, corresponding to amino acids 525-663 of Human PDE4DIP.

  • Positive control
    • Human rectum tissue; RT 4, U 251 MG, Human liver and Human tonsil lysates.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab121275 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • FunctionMay function as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.
  • Tissue specificityHighly expressed in heart and skeletal muscle and to a lower extent in brain and placenta.
  • Involvement in diseaseNote=A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
  • Sequence similaritiesContains 1 NBPF domain.
  • Developmental stageExpressed in fetal heart.
  • Cellular localizationGolgi apparatus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • Cardiomyopathy associated protein 2 antibody
    • Cardiomyopathy-associated protein 2 antibody
    • CMYA2 antibody
    • MMGL antibody
    • MYOME_HUMAN antibody
    • Myomegalin antibody
    • Pde4dip antibody
    • Phosphodiesterase 4D interacting protein antibody
    • Phosphodiesterase 4D-interacting protein antibody
    see all

Anti-PDE4DIP antibody images

  • All lanes : Anti-PDE4DIP antibody (ab121275) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique
  • ab121275 at 1/40 dilution staining PDE4DIP in Paraffin-embedded Human Rectum tissue by Immunohistochemistry.

References for Anti-PDE4DIP antibody (ab121275)

ab121275 has not yet been referenced specifically in any publications.

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