Overview

  • Product nameAnti-PDE6 alpha antibody
    See all PDE6 alpha primary antibodies
  • Description
    Rabbit polyclonal to PDE6 alpha
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Sheep, Cow
    Predicted to work with: Mouse, Chicken, Human
  • Immunogen

    Synthetic peptide corresponding to Human PDE6C aa 16-29.
    Sequence:

    MPQFAKEYFDRKLR


    (Peptide available as ab5863)

  • Positive control
    • WB: sheep retinal extract.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab5660 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500. Detects a band of approximately 90 kDa.Can be blocked with PDE6C peptide (ab5863).

Target

  • FunctionThis protein participates in processes of transmission and amplification of the visual signal.
  • Involvement in diseaseDefects in PDE6A are the cause of retinitis pigmentosa type 43 (RP43) [MIM:613810]. RP43 is a retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
  • Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family.
    Contains 2 GAF domains.
  • Cellular localizationCell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5''-cyclic phosphodiesterase subunit alpha antibody
    • CGPR A antibody
    • GMP PDE alpha antibody
    • GMP-PDE alpha antibody
    • PDE 6 alpha antibody
    • PDE 6A antibody
    • PDE V B1 antibody
    • PDE V-B1 antibody
    • PDE6A antibody
    • PDE6A_HUMAN antibody
    • PDEA antibody
    • Phosphodiesterase 6 alpha antibody
    • Phosphodiesterase 6A alpha subunit antibody
    • Phosphodiesterase 6A cGMP specific rod alpha antibody
    • Retinal Rod Photoreceptor cGMP Phosphodiesterase alpha antibody
    • Rod cGMP specific 3' 5' cyclic phosphodiesterase alpha subunit antibody
    • Rod cGMP-specific 3'' antibody
    see all

Anti-PDE6 alpha antibody images

  • Western blot of PDE6C on sheep retinal extracts using ab5660.

References for Anti-PDE6 alpha antibody (ab5660)

ab5660 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab5660.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"