Anti-PDE8A antibody (ab61815)
Key features and details
- Rabbit polyclonal to PDE8A
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-PDE8A antibody
See all PDE8A primary antibodies -
Description
Rabbit polyclonal to PDE8A -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human PDE8A (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).
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Positive control
- Human prostate tissue
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.70
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab61815 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 10 µg/ml.
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Notes |
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IHC-P
Use a concentration of 10 µg/ml. |
Target
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Function
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. -
Tissue specificity
Expressed in most tissues except thymus and peripheral blood leukocytes. Highest levels in testis, ovary, small intestine and colon. -
Pathway
Purine metabolism; 3',5'-cyclic AMP degradation; AMP from 3',5'-cyclic AMP: step 1/1. -
Sequence similarities
Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
Contains 1 PAC (PAS-associated C-terminal) domain.
Contains 1 PAS (PER-ARNT-SIM) domain. -
Domain
Composed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain. - Information by UniProt
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Database links
- Entrez Gene: 5151 Human
- Omim: 602972 Human
- SwissProt: O60658 Human
- Unigene: 9333 Human
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Alternative names
- 5''-cyclic phosphodiesterase 8A antibody
- cAMP specific cyclic nucleotide phosphodiesterase 8A antibody
- FLJ16150 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab61815 has not yet been referenced specifically in any publications.