Overview

  • Product nameAnti-PDE9A antibody
    See all PDE9A primary antibodies
  • Description
    Rabbit polyclonal to PDE9A
  • Tested applicationsSuitable for: WB, IHC-P, IPmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide, corresponding to amino acids at the C-terminal of Human PDE9A.

  • Positive control
    • Insect cells transfected with Human PDE9A.

Properties

Applications

Our Abpromise guarantee covers the use of ab125672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000 - 1/5000. Predicted molecular weight: 68 kDa.
IHC-P Use at an assay dependent concentration.
IP Use at an assay dependent concentration.

Target

  • FunctionHydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes.
  • Tissue specificityExpressed in all tissues examined (testis, brain, small intestine, skeletal muscle, heart, lung, thymus, spleen, placenta, kidney, liver, pancreas, ovary and prostate) except blood. Highest levels in brain, heart, kidney, spleen, prostate and colon. Isoform PDE9A12 is found in prostate.
  • Sequence similaritiesBelongs to the cyclic nucleotide phosphodiesterase family. PDE9 subfamily.
  • DomainComposed of a C-terminal catalytic domain containing two putative divalent metal sites and an N-terminal regulatory domain.
  • Cellular localizationCytoplasm. Endoplasmic reticulum; Cell projection > ruffle membrane. Cytoplasm > perinuclear region and Cell projection > ruffle membrane. Cytoplasm > perinuclear region. Golgi apparatus. Endoplasmic reticulum.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5''-cyclic phosphodiesterase 9A antibody
    • cGMP specific 3' 5' cyclic phosphodiesterase type 9 antibody
    • FLJ90181 antibody
    • High affinity cGMP-specific 3'' antibody
    • High-affinity cGMP-specific 3'5'-cyclic phosphodiesterase 9A antibody
    • HSPDE9A2 antibody
    • OTTHUMP00000109399 antibody
    • PDE 9A antibody
    • Pde9a antibody
    • PDE9A_HUMAN antibody
    • Phosphodiesterase 9A antibody
    • phosphodiesterase PDE9A21 antibody
    see all

Anti-PDE9A antibody images

  • All lanes : Anti-PDE9A antibody (ab125672) at 1/2000 dilution

    Lane 1 : Insect cells, transfected with Human PDE1A3
    Lane 2 : Insect cells transfected with Human PDE2A3
    Lane 3 : Insect cells, transfected with Human PDE3A
    Lane 4 : Insect cells, transfected with Human PDE4A1
    Lane 5 : Insect cells, transfected with Human PDE5A2
    Lane 6 : Insect cells, transfected with Human PDE7A
    Lane 7 : Insect cells, transfected with Human PDE8A1
    Lane 8 : Insect cells, transfected with Human PDE8B
    Lane 9 : Insect cells transfected with Human PDE9A2
    Lane 10 : Insect cells, transfected with Human PDE10A1
    Lane 11 : Insect cells, transfected with Human PDE11A1

    Developed using the ECL technique

    Predicted band size : 68 kDa

References for Anti-PDE9A antibody (ab125672)

ab125672 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Brain)
Permeabilization Yes - Triton X-100
Specification Brain
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
Fixative Paraformaldehyde
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Submitted Jul 11 2016

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"