Overview

  • Product nameAnti-PDGF AB + BB antibody
  • Description
    Goat polyclonal to PDGF AB + BB
  • SpecificityRecognizes non-reduced human PDGF AA, AB and BB dimers in western immunoblots. Porcine and bovine PDGF may be detected with decreased sensitivity. Rodent PDGF will not be detected. This antibody will neutralize human, porcine, bovine and rodent PDGF.
  • Tested applicationsSuitable for: WB, Neutralisingmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Cow, Human, Pig
  • Immunogen

    Purified human PDGF-AB

  • Positive control
    • 3T3 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab34074 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
Neutralising
  • Application notesNeut: Use at a concentration of 10 - 20 µg/ml. In a 5 day assay, 10-20ug/ml inhibited 3T3 cell growth by 60-75% as stimulated by 10ng/ml of PDGF-AB.
    WB: Use at a concentration of 5 - 10 µg/ml. Predicted molecular weight: 124 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevancePlatelet-Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.
    • Cellular localizationSecreted
    • Database links
    • Alternative names
      • Becaplermin antibody
      • c sis antibody
      • FLJ1285 antibody
      • Oncogene SIS antibody
      • PDGF 1 antibody
      • PDGF 2 antibody
      • PDGF A antibody
      • PDGF A chain antibody
      • PDGF B chain antibody
      • PDGF subunit A antibody
      • PDGF subunit B antibody
      • PDGF1 antibody
      • PDGF2 antibody
      • PDGFA antibody
      • PDGFB antibody
      • Platelet derived growth factor 2 antibody
      • Platelet derived growth factor alpha antibody
      • Platelet derived growth factor alpha chain antibody
      • Platelet derived growth factor alpha polypeptide antibody
      • Platelet derived growth factor B chain antibody
      • Platelet derived growth factor beta antibody
      • Platelet derived growth factor beta polypeptide antibody
      • Platelet derived growth factor subunit A antibody
      • Platelet derived growth factor subunit B antibody
      • SIS antibody
      • SSV antibody
      • v sis platelet derived growth factor beta polypeptide antibody
      see all

    References for Anti-PDGF AB + BB antibody (ab34074)

    This product has been referenced in:
    • Song CH  et al. Identification of chemoattractive factors involved in the migration of bone marrow-derived mesenchymal stem cells to brain lesions caused by prions. J Virol 85:11069-78 (2011). Read more (PubMed: 21813601) »

    See 1 Publication for this product

    Product Wall

    This PDGF antibody was raised against purified PDGF from human platelets.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"