You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

PDGF BB protein (Active) (ab9706)

CodeSizePriceAbpointsAvailability
    
Add to basket
 

  • -

  •   
  •   
  •   

  •  

  •  
  •  

  •  

  •  
Updating...

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »

Overview

Product name

PDGF BB protein (Active)
See all PDGF BB products (9) ...

Protein description

Highly pure (>98%) recombinant human PDGF-BB (Platelet-Derived Growth Factor-BB)

Expression host

E. coli

Properties

Purity

> 95% by SDS-PAGE

Purification notes

Sterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Form

Lyophilised

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

This product is an active protein and may elicit a biological response in vivo, handle with caution.

Concentration

Concentration information loading...

Additional notes

Biological Activity is determined by the dose-dependent stimulation of the proliferation of BALB/c 3T3 cells is < 1.0 ng/ml, corresponding to a specific activity of > 1 x 106 units/mg

Sequence notes

Human PDGF-BB is a 24.3 kDa B chain homodimer protein containing 109 amino acid residues: SLGSLTIAEP AMIAECKTRT EVFEISRRLI DRTNANFLVW PPCVEV QRCS GCCNNRNVQCRPTQVQLRPV QVRKIGIVRK KPI FKKATVT LGDHLACKCE TVAAARPVT

Research areas

Metabolism >> Types of disease >> Heart disease
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolism processes >> Hypoxia
Stem Cells >> Stem Cell Cytokines >> Recombinant Human
Cancer >> Cancer Metabolism >> Response to hypoxia
Developmental Biology >> Organogenesis >> Angiogenesis and vasculogenesis
Cardiovascular >> Atherosclerosis >> Vascular Inflammation >> Inflammatory mediators
Cancer >> Growth factors >> PDGF
Signal Transduction >> Growth Factors/Hormones >> PDGF
Cardiovascular >> Blood >> Serum Proteins

Applications

Show applications key

Our Abpromise guarantee covers the use of ab9706 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    Functional Studies

     FuncS: Use at an assay d...Read more →

    FuncS: Use at an assay dependent dilution. Activity of ab9706 was determined by the dose-dependent stimulation of the proliferation of Balb/c 3T3 cells (ED501.0-3.0 ng/ml).

  • ShowHide

    SDS-PAGE

     SDS-PAGE: Use at an ass...Read more →

    SDS-PAGE: Use at an assay dependent dilution.

Application notes

This peptide can be used with studies using ab9704.

Protein info

Target information above from: UniProt accessionP01127 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for PDGF BB protein (Active) (ab9706)

ab9706 has not yet been referenced specifically in any publications.

Publishing research using ab9706? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"