• Product name
    Anti-PDGFAA + PDGFBB antibody
  • Description
    Goat polyclonal to PDGFAA + PDGFBB
  • Specificity
    The antibody reacts with PKBa. It may recognize the PKBß isoform. The sequence is identical in mouse, rat, and bovine PKBa, highly conserved in PKBß, and diverges in the PKB? isoform.
  • Tested applications
    Suitable for: WB, Neutralising, Indirect ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Natural human PDGF

  • Positive control
    • PDGF-responsive NR6R-3T3 fibroblasts.



Our Abpromise guarantee covers the use of ab50201 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Indirect ELISA
  • Application notes
    I-ELISA: Use at a concentration of 0.25 µg/ml.
    Neut: Use at an assay dependent dilution.
    WB: Use at a concentration of 1 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
    • Tissue specificity
      Expressed at high levels in the heart, brain (sustantia nigra), placenta and fetal kidney. Expressed at moderate levels in the brain (hippocampus), skeletal muscle, kidney and lung.
    • Involvement in disease
      Note=A chromosomal aberration involving PDGFB is found in dermatofibrosarcoma protuberans. Translocation t(17;22)(q22;q13) with PDGF.
    • Sequence similarities
      Belongs to the PDGF/VEGF growth factor family.
    • Cellular localization
    • Information by UniProt
    • Database links
    • Form
      PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Secreted.
    • Alternative names
      • becaplermin antibody
      • c-sis antibody
      • FLJ12858 antibody
      • PDGF 1 antibody
      • PDGF 2 antibody
      • PDGF B antibody
      • PDGF B chain antibody
      • PDGF subunit B antibody
      • PDGF-2 antibody
      • Pdgfb antibody
      • PDGFB_HUMAN antibody
      • Platelet derived growth factor beta polypeptide antibody
      • platelet-derived growth factor 2 antibody
      • Platelet-derived growth factor B chain antibody
      • Platelet-derived growth factor beta polypeptide antibody
      • Platelet-derived growth factor subunit B antibody
      • Platelet-derived growth factor, beta polypeptide (oncogene SIS) antibody
      • Proto-oncogene c-Sis antibody
      • SIS antibody
      • SSV antibody
      see all

    References for Anti-PDGFAA + PDGFBB antibody (ab50201)

    This product has been referenced in:
    • Baghy K  et al. Decorin interferes with platelet-derived growth factor receptor signaling in experimental hepatocarcinogenesis. FEBS J 280:2150-64 (2013). Read more (PubMed: 23448253) »

    See 1 Publication for this product

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