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Rabbit polyclonal to PDHX - C-terminal
Synthetic peptide, corresponding to a region within C terminal amino acids 438-501 of Human PDHX (Uniprot ID: O00330).
A431, H1299, HeLa and HepG2 whole cell lysates.
Keep as concentrated solution.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 89% PBS, 10% Glycerol
Concentration information loading...
Immunogen affinity purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 54 kDa.
Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
Involvement in disease
Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:245349].
Belongs to the 2-oxoacid dehydrogenase family.
Contains 1 lipoyl-binding domain.
Information by UniProt
Dihydrolipoamide dehydrogenase binding protein of pyruvate dehydrogenase complex antibody
Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex antibody
has not yet been referenced specifically in any publications.
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