• Product nameAnti-PDLIM7 antibody
    See all PDLIM7 primary antibodies
  • Description
    Mouse monoclonal to PDLIM7
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-458 of Human PDLIM7



Our Abpromise guarantee covers the use of ab56504 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway.
    • Tissue specificityIsoform 1 and isoform 2 are expressed ubiquitously, however, isoform 2 predominates in skeletal muscle, isoform 1 is more abundant in lung, spleen, leukocytes and fetal liver.
    • Sequence similaritiesContains 3 LIM zinc-binding domains.
      Contains 1 PDZ (DHR) domain.
    • DomainThe LIM zinc-binding 2 (LIM 2) domain interacts with TBX4.
      The LIM zinc-binding 3 (LIM 3) domain provides the structural basis for recognition of tyrosine-containing tight turn structures. This domain is necessary and sufficient for interaction with TBX5.
      Anchored to cell periphery via its N-terminal PDZ domain.
    • Cellular localizationCytoplasm. Cytoplasm > cytoskeleton. Colocalizes with RET to the cell periphery and in some cytoskeletal components. Colocalizes with TPM2 near the Z line in muscle. Co-localizes with TBX4 and TBX5 to actin filaments.
    • Information by UniProt
    • Database links
    • Alternative names
      • 1110003B01Rik antibody
      • Enigma antibody
      • LIM domain protein antibody
      • LIM domain protein enigma antibody
      • LIM mineralization protein 1 antibody
      • Lim mineralization protein 3 antibody
      • LIM mineralization protein antibody
      • LMP 1 antibody
      • LMP antibody
      • LMP1 antibody
      • LMP3 antibody
      • PDLI7_HUMAN antibody
      • PDLIM 7 antibody
      • Pdlim7 antibody
      • PDZ and LIM doamin protein 7 antibody
      • PDZ and LIM domain 7 antibody
      • PDZ and LIM domain protein 7 antibody
      • Protein enigma antibody
      see all

    Anti-PDLIM7 antibody images

    • Predicted band size : 21 kDa
      PDLIM7 antibody (ab56504) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    References for Anti-PDLIM7 antibody (ab56504)

    This product has been referenced in:
    • Yi CR  et al. Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins. J Biol Chem 289:30101-13 (2014). Read more (PubMed: 25124035) »

    See 1 Publication for this product

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