Overview

  • Product nameAnti-PDSS2 antibody [4F9]
    See all PDSS2 primary antibodies
  • Description
    Mouse monoclonal [4F9] to PDSS2
  • Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein of Human PDSS2 produced in HEK293T cells (NP_065114).

  • Positive control
    • HEK293T cells transfected with PDSS2, Adenocarcinoma of Human ovary tissue, COS7 cells transiently transfected with PDSS2
  • General notesDilute in PBS (pH7.3) before use.

Properties

Applications

Our Abpromise guarantee covers the use of ab119804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/2000. Predicted molecular weight: 44 kDa.
IHC-P 1/150.
ICC/IF 1/100.

Target

  • FunctionSupplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
  • PathwayCofactor biosynthesis; ubiquinone biosynthesis.
  • Involvement in diseaseDefects in PDSS2 are a cause of coenzyme Q10 deficiency (COQ10D) [MIM:607426]. Coenzyme Q10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.
  • Sequence similaritiesBelongs to the FPP/GGPP synthase family.
  • Cellular localizationMitochondrion.
  • Information by UniProt
  • Database links
  • Alternative names
    • All-trans-decaprenyl-diphosphate synthase subunit 2 antibody
    • bA59I9.3 antibody
    • C6orf210 antibody
    • Candidate tumor suppressor protein antibody
    • chromosome 6 open reading frame 210 antibody
    • Decaprenyl pyrophosphate synthase subunit 2 antibody
    • decaprenyl pyrophosphate synthetase subunit 2 antibody
    • Decaprenyl-diphosphate synthase subunit 2 antibody
    • DLP1 antibody
    • DLP1_HUMAN antibody
    • hDLP1 antibody
    • Pdss2 antibody
    • prenyl (decaprenyl) diphosphate synthase, subunit 2 antibody
    • subunit 2 of decaprenyl diphosphate synthase antibody
    see all

Anti-PDSS2 antibody [4F9] images

  • All lanes : Anti-PDSS2 antibody [4F9] (ab119804) at 1/2000 dilution

    Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control
    Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PDSS2

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 44 kDa
    HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC207892)
  • Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using ab119804 at a dilution of 1/150.
  • Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDSS2 using ab119804 at a dilution of 1/100.

References for Anti-PDSS2 antibody [4F9] (ab119804)

ab119804 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab119804.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"