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Storage instructions Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer pH: 7.30 Preservative: 0.02% Sodium azide Constituents: 48% PBS, 50% Glycerol, 1% BSA
Concentration information loading...
Purity Protein A purified
Clone number OTI4F9
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000. Predicted molecular weight: 44 kDa.
Function Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10.
Pathway Cofactor biosynthesis; ubiquinone biosynthesis.
Involvement in disease Defects in PDSS2 are a cause of coenzyme Q10 deficiency (COQ10D) [MIM:607426]. Coenzyme Q10 deficiency is an autosomal recessive disorder with variable manifestations. It can be associated with three main clinical phenotypes: a predominantly myopathic form with central nervous system involvement, an infantile encephalomyopathy with renal dysfunction and an ataxic form with cerebellar atrophy.
Sequence similarities Belongs to the FPP/GGPP synthase family.
Cellular localization Mitochondrion.
Information by UniProt
All-trans-decaprenyl-diphosphate synthase subunit 2 antibody
Anti-PDSS2 antibody [OTI4F9] images
Western blot - Anti-PDSS2 antibody [OTI4F9] (ab119804)
All lanes : Anti-PDSS2 antibody [OTI4F9] (ab119804) at 1/2000 dilution Lane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY control Lane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY PDSS2 Lysates/proteins at 5 µg per lane. Predicted band size : 44 kDa HEK293T cell lysates were generated from transient transfection of the cDNA clone (RC207892)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PDSS2 antibody [OTI4F9] (ab119804)
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using ab119804 at a dilution of 1/150.
Immunocytochemistry/ Immunofluorescence - Anti-PDSS2 antibody [OTI4F9] (ab119804)
Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDSS2 using ab119804 at a dilution of 1/100.
References for Anti-PDSS2 antibody [OTI4F9] (ab119804)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"