Overview

  • Product nameAnti-PDZD3 antibody
    See all PDZD3 primary antibodies
  • Description
    Mouse polyclonal to PDZD3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant full length protein, corresponding to amino acids 1-493 of Human PDZD3

  • Positive control
    • SOX18 transfected 293T cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab66146 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: 1/500 - 1/1000. Detects a band of approximately 54 kDa (predicted molecular weight: 61 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionActs as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
    • Tissue specificityExpressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin.
    • Sequence similaritiesContains 4 PDZ (DHR) domains.
    • Cellular localizationCell membrane. Cytoplasm. Preferentially accumulates at the apical surface and ileal brush border of intestinal epithelial cells.
    • Information by UniProt
    • Database links
    • Alternative names
      • IKEPP antibody
      • Intestinal and kidney enriched PDZ protein antibody
      • Intestinal and kidney-enriched PDZ protein antibody
      • Na(+)/H(+) exchange regulatory cofactor NHE-RF4 antibody
      • Na/Pi cotransporter C terminal associated protein 2 antibody
      • Na/Pi cotransporter C-terminal-associated protein 2 antibody
      • NaPi-Cap2 antibody
      • Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 antibody
      • NHERF-4 antibody
      • NHERF4 antibody
      • NHRF4_HUMAN antibody
      • PDZ domain containing 2 antibody
      • PDZ domain containing 3 antibody
      • PDZ domain containing protein 2 antibody
      • PDZ domain-containing protein 2 antibody
      • PDZ domain-containing protein 3 antibody
      • PDZD 3 antibody
      • Pdzd3 antibody
      • PDZK2 antibody
      • Protein DLNB27 antibody
      • Sodium-hydrogen exchanger regulatory factor 4 antibody
      see all

    Anti-PDZD3 antibody images

    • All lanes : Anti-PDZD3 antibody (ab66146) at 1/500 dilution

      Lane 1 : PDZD3 transfected 293T cell lysate
      Lane 2 : Non-transfected 293T cell lysate

      Lysates/proteins at 25 µg per lane.

      Secondary
      Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

      Predicted band size : 41 kDa
      Observed band size : 54 kDa (why is the actual band size different from the predicted?)

    References for Anti-PDZD3 antibody (ab66146)

    ab66146 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"