• Product nameAnti-Peg3 antibody
    See all Peg3 primary antibodies
  • Description
    Rabbit polyclonal to Peg3
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Synthetic peptide conjugated to KLH derived from within residues 1300 - 1400 of Mouse Peg3.

    (Peptide available as ab109925.)

  • Positive control
    • This antibody gave a positive signal in both Mouse and Rat skeletal muscle tissue lysates.



Our Abpromise guarantee covers the use of ab99252 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Detects a band of approximately 179 kDa (predicted molecular weight: 179 kDa).


  • RelevancePeg3 encodes a C2H2 type zinc finger protein that is implicated in regulating core body temperature, feeding behavior and obesity in mice. The Peg3 gene transcript encodes a zinc finger protein of 1,572 amino acids. Peg3 is expressed in early somites, branchial arches, and other mesodermal tissues, as well as in the hypothalamus. PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells. GENE FUNCTION Kim et al. (1997) reported that the PEG3 gene, like other genes within the region on 19q to which it maps, also encodes a Kruppel-type ZNF protein, but one that is distinguished from other ZNF gene products by the fact that it carries 2 novel proline-rich motifs. The mouse and partial human PEG3 gene sequences showed a high level of conservation, despite that fact that 1 of the 2 proline-rich repeats is absent from the human gene. Kim et al. (1997) found that the human gene is expressed at highest levels in ovary and placenta; mouse Peg3, by contrast, is transcribed at highest levels in the adult brain.
  • Cellular localizationNuclear
  • Database links
  • Alternative names
    • Kruppel-type zinc finger protein antibody
    • paternally expressed 3 antibody
    • Paternally expressed gene 3 antibody
    • Paternally expressed gene 3 protein antibody
    • PEG3 protein antibody
    • Pw1 antibody
    • Zinc finger and SCAN domain containing protein 24 antibody
    • ZKSCAN22 antibody
    • Zn-finger protein Pw1 antibody
    • ZNF904 antibody
    • ZSCAN24 antibody
    see all

Anti-Peg3 antibody images

  • All lanes : Anti-Peg3 antibody (ab99252) at 1 µg/ml

    Lane 1 : Skeletal Muscle (Mouse) Tissue Lysate
    Lane 2 : Skeletal Muscle (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 179 kDa
    Observed band size : 179 kDa
    Additional bands at : 105 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 3 minutes

References for Anti-Peg3 antibody (ab99252)

This product has been referenced in:
  • Ye A  et al. Paternally expressed Peg3 controls maternally expressed Zim1 as a trans factor. PLoS One 9:e108596 (2014). ChIP ; Mouse . Read more (PubMed: 25265264) »
  • Buraschi S  et al. Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. PLoS One 7:e45559 (2012). WB . Read more (PubMed: 23029096) »

See all 2 Publications for this product

Product Wall

Thank you for kindly confirming these details as this enables us to closely monitor the quality of our products

We would be pleased to arrange a replacement product free of charge with the order #######

Thank you for your help and...

Read More

Thank you for your reply.

Just to make sure I understood you correctly: the customer would like an alternative Anti-Peg3 antibody as a free of charge replacement?

Thank you for checking this.