Overview

  • Product name
  • Description
    Rabbit polyclonal to PELI3
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Pig
  • Immunogen

    Synthetic peptide (Human)

  • Positive control
    • HepG2 cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab76034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 48 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • Function
    Scaffold protein which probably links Toll-like receptors (TLRs) to basic cellular processes via its interaction with the complex containing IRAK kinases and TRAF6. Can activate AP1/JUN and ELK1. Not required for NF-kappa-B activation. Probably involved in innate immune response.
  • Tissue specificity
    Highly expressed in brain, heart and testis, and at lower level in kidney, liver, lung, placenta, small intestine, spleen and stomach. Isoform 1 is not expressed in lung.
  • Sequence similarities
    Belongs to the pellino family.
  • Information by UniProt
  • Database links
  • Alternative names
    • E3 ubiquitin protein ligase pellino homolog 3 antibody
    • MGC35521 antibody
    • PEL 13 antibody
    • Peli3 antibody
    • PELI3_HUMAN antibody
    • Pellino 3 antibody
    • Pellino 3 alpha antibody
    • Pellino E3 ubiquitin protein ligase family member 3 antibody
    • Pellino homolog 3 (Drosophila) antibody
    • Pellino-3 antibody
    • Protein pellino homolog 3 antibody
    see all

Images

  • Anti-PELI3 antibody (ab76034) at 1 µg/ml (in 5% skim milk / PBS buffer) + HepG2 cell lysate at 10 µg

    Secondary
    HRP-conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 48 kDa
    Observed band size : 40 kDa (why is the actual band size different from the predicted?)

References

ab76034 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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