Anti-Pellino 1 antibody - C-terminal (ab189953)

Overview

  • Product name
    Anti-Pellino 1 antibody - C-terminal
    See all Pellino 1 primary antibodies
  • Description
    Rabbit polyclonal to Pellino 1 - C-terminal
  • Tested applications
    Suitable for: ICC/IF, WB, IHC-P, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Pellino 1 (C terminal). (15 amino acid peptide near the carboxy terminus; NP_065702.2).
    Database link: Q96FA3

  • Positive control
    • Human tonsil tissue; HepG2 cells; Human liver tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab189953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 46 kDa.
IHC-P Use a concentration of 5 µg/ml.
ICC Use a concentration of 2.5 µg/ml.

Target

  • Function
    Scaffold protein involved in the IL-1 signaling pathway via its interaction with the complex containing IRAK kinases and TRAF6. Required for NF-kappa-B activation and IL-8 gene expression in response to IL-1.
  • Sequence similarities
    Belongs to the pellino family.
  • Information by UniProt
  • Database links
  • Alternative names
    • E3 ubiquitin-protein ligase pellino homolog 1 antibody
    • PELI1 antibody
    • PELI1_HUMAN antibody
    • Pellino E3 ubiquitin protein ligase 1 antibody
    • Pellino homolog 1 antibody
    • Pellino protein antibody
    • Pellino-1 antibody
    • Pellino-related intracellular-signaling molecule antibody
    • Pellino1 antibody
    • PRISM antibody
    • Protein pellino homolog 1 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human tonsil tissue labeling Pellino 1 with ab189953 at 5 µg/ml.

  • Immunofluorescent analysis of HepG2 cells labeling Pellino 1 with ab189953 at 20 µg/ml.

  • Immunocytochemical analysis of HepG2 cells labeling Pellino 1 with ab189953 at 2.5 µg/ml.

  • Lane 1 : Anti-Pellino 1 antibody - C-terminal (ab189953) at 1 µg/ml
    Lane 2 : Anti-Pellino 1 antibody - C-terminal (ab189953) at 2 µg/ml

    Lane 1 : Human liver tissue lysate
    Lane 2 : Human liver tissue lysate


    Predicted band size : 46 kDa

References

ab189953 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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