Overview

  • Product name
  • Description
    Mouse polyclonal to PELO
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    PELO full-length human protein (AAH05889.1, aa 1-385)

  • Positive control
    • Human stomach lysate, Hela cell lysate and PELO transfected 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab88673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

Target

  • Function
    Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
  • Domain
    The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CGI 17 antibody
    • CGI17 antibody
    • pelo antibody
    • PELO_HUMAN antibody
    • pelota (Drosophila) homolog antibody
    • pelota homolog antibody
    • PRO1770 antibody
    • Protein pelota homolog antibody
    see all

Anti-PELO antibody images

  • Anti-PELO antibody (ab88673) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • Anti-PELO antibody (ab88673) at 1 µg/ml + Hela cell lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • All lanes : Anti-PELO antibody (ab88673) at 1 µg/ml

    Lane 1 : PELO transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

References for Anti-PELO antibody (ab88673)

ab88673 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab88673.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up