Overview

  • Product name
  • Description
    Mouse polyclonal to PELO
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    PELO full-length human protein (AAH05889.1, aa 1-385)

  • Positive control
    • Human stomach lysate, Hela cell lysate and PELO transfected 293T cell lysate

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab88673 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 43 kDa.

Target

  • Function
    Required for normal chromosome segregation during cell division and genomic stability (By similarity). May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs. May have ribonuclease activity.
  • Tissue specificity
    Ubiquitously expressed.
  • Sequence similarities
    Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
  • Domain
    The N-terminal domain has the RNA-binding Sm fold. It may harbor the endoribonuclease activity.
  • Cellular localization
    Nucleus. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CGI 17 antibody
    • CGI17 antibody
    • pelo antibody
    • PELO_HUMAN antibody
    • pelota (Drosophila) homolog antibody
    • pelota homolog antibody
    • PRO1770 antibody
    • Protein pelota homolog antibody
    see all

Images

  • Anti-PELO antibody (ab88673) at 1 µg/ml + Human stomach lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • Anti-PELO antibody (ab88673) at 1 µg/ml + Hela cell lysate at 50 µg

    Predicted band size : 43 kDa
    Observed band size : 43 kDa
  • All lanes : Anti-PELO antibody (ab88673) at 1 µg/ml

    Lane 1 : PELO transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 43 kDa
    Observed band size : 43 kDa

References

ab88673 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab88673.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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