Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum as well as purified and partially purified Penicillinase [E. clocae]. Cross reactivity against Penicillinase from other tissues and species may occur but have not been specifically determined.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: 1/7000 - 1/21000 in assay against 1.0ug of Penicillinase [E. clocae] in a standard ELISA.
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Penicillinase is a beta-lactamase, showing specificity for penicillins by hydrolysing the beta-lactam ring. Beta lactamases play a significant role in the high resistance of certain organinsms to penicillins, cephalosporins, cephamycins and carbapenems. These antibiotics have a common element in their molecular structure: a four-atom ring known as a beta-lactam. The lactamase enzyme breaks that ring open, deactivating the molecule's antibacterial properties. Penicillinase resistant ß lactams have been developed, such as methicillin, although there is widespread resistance to these now also (MRSA).
Aer 1 antibody
Beta lactamase 1 antibody
Beta lactamase AER 1 antibody
Beta lactamase AER1 antibody
Beta lactamase antibody
Beta lactamase type I antibody
Bla L antibody
OXA 9 antibody
References for Anti-Penicillinase antibody (ab20959)
has not yet been referenced specifically in any publications.
Publishing research using ab20959? Please let us know so that we can cite the reference in this datasheet.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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