• Product nameAnti-Pericentrin antibody
    See all Pericentrin primary antibodies
  • Description
    Rabbit polyclonal to Pericentrin
  • Tested applicationsSuitable for: IP, ICC/IF, ICCmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide, corresponding to a region within amino acids 175-225 of Human Pericentrin (NP_006022.3).

  • Positive control
    • HeLa whole cell lysate


Associated products


Our Abpromise guarantee covers the use of ab99341 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
ICC/IF 1/1000 - 1/5000.
ICC 1/1000 - 1/5000.

Formaldehyde or Acetone fixation is recommended. Permeabilization with Triton-X 100 is recommended for formaldehydefixed cells.

  • Application notesIs unsuitable for WB.
  • Target

    • FunctionIntegral component of the filamentous matrix of the centrosome involved in the initial establishment of organized microtubule arrays in both mitosis and meiosis. Plays a role, together with DISC1, in the microtubule network formation. Is an integral component of the pericentriolar material (PCM). May play an important role in preventing premature centrosome splitting during interphase by inhibiting NEK2 kinase activity at the centrosome.
    • Tissue specificityExpressed in all tissues tested, including placenta, liver, kidney and thymus.
    • Involvement in diseaseMicrocephalic osteodysplastic primordial dwarfism 2
    • DomainComposed of a coiled-coil central region flanked by non-helical N- and C-terminals.
    • Cellular localizationCytoplasm > cytoskeleton > microtubule organizing center > centrosome. Centrosomal at all stages of the cell cycle. Remains associated with centrosomes following microtubule depolymerization. Colocalized with DISC1 at the centrosome.
    • Information by UniProt
    • Database links
    • Alternative names
      • Centrosome Marker antibody
      • Ken antibody
      • Kendrin antibody
      • KIAA0402 antibody
      • MOPD2 antibody
      • PCN antibody
      • PCNT 2 antibody
      • PCNT antibody
      • PCNT B antibody
      • PCNT_HUMAN antibody
      • PCNT1 antibody
      • PCNT2 antibody
      • PCNTB antibody
      • PCTN2 antibody
      • Pericentrin 1 antibody
      • Pericentrin 2 antibody
      • Pericentrin 380 antibody
      • Pericentrin antibody
      • Pericentrin B antibody
      • Pericentrin-B antibody
      • SCKL4 antibody
      see all

    Anti-Pericentrin antibody images

    • Immunocytochemistry/Immunofluorescence analysis of formaldehyde-fixed asynchronous HeLa cells labelling Pericentrin with ab99341 at 1/1000 (1µg/ml). A DyLight® 594-conjugated goat anti-rabbit IgG (H+L) (1/100) was used as the secondary antibody.
    • Detection of Pericentrin by Western Blot of Immunoprecipitates in HeLa whole cell lysate (1 mg for IP, 20% of IP loaded) using ab99341 at 3 µg/mg lysate. Anti-Pericentrin antibody ab99342, which recognizes a downstream epitope, was used at 1 µg/ml for subsequent WB detection.

    References for Anti-Pericentrin antibody (ab99341)

    ab99341 has not yet been referenced specifically in any publications.

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