Recombinant
RabMAb

Anti-Perilipin-1 antibody [EPR3753(2)] (ab172907)

Overview

  • Product name
    Anti-Perilipin-1 antibody [EPR3753(2)]
    See all Perilipin-1 primary antibodies
  • Description
    Rabbit monoclonal [EPR3753(2)] to Perilipin-1
  • Tested applications
    Suitable for: WB, ICC/IFmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity
    Reacts with: Mouse, Human
    Does not react with: Rat
  • Immunogen

    Synthetic peptide within Human Perilipin-1 aa 450 to the C-terminus (Cysteine residue). The exact sequence is proprietary.
    Database link: O60240

  • Positive control
    • Fetal heart, adipose tissue and feral liver lysates, HepG2 cells
  • General notes

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab172907 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/5000. Predicted molecular weight: 62 kDa.
ICC/IF 1/100 - 1/250.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function
      Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
    • Tissue specificity
      Adipocytes.
    • Sequence similarities
      Belongs to the perilipin family.
    • Post-translational
      modifications
      Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
    • Cellular localization
      Lipid droplet. Lipid droplet surface-associated.
    • Information by UniProt
    • Database links
    • Alternative names
      • Lipid droplet associated protein antibody
      • Lipid droplet-associated protein antibody
      • PERI antibody
      • Perilipin A antibody
      • Perilipin antibody
      • Perilipin-1 antibody
      • PerilipinA antibody
      • PLIN antibody
      • PLIN1 antibody
      • PLIN1_HUMAN antibody
      see all

    Images

    • Immunofluorescent analysis of HepG2 cells labeling Perilipin-1 with ab172907 at 1/100 (red) and counterstained with DAPI (blue).

    • Lane 1 : Anti-Perilipin-1 antibody [EPR3753(2)] (ab172907) at 1/2000 dilution
      Lanes 2 - 3 : Anti-Perilipin-1 antibody [EPR3753(2)] (ab172907) at 1/10000 dilution

      Lane 1 : Fetal heart
      Lane 2 : Human adipose
      Lane 3 : Fetal liver

      Lysates/proteins at 10 µg per lane.


      Predicted band size : 62 kDa

    References

    ab172907 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab172907.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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