Overview

  • Product nameAnti-Perilipin A antibody
    See all Perilipin A primary antibodies
  • Description
    Goat polyclonal to Perilipin A
  • Tested applicationsSuitable for: WB, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Cow, Pig, Chimpanzee, Rhesus monkey
  • Immunogen

    Synthetic peptide:

    C-PREKPKRRVSDS

    , corresponding to iamino acids 488-499 of Human Perilipin

  • Positive control
    • Human Adipose tissue lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab60269 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.01 µg/ml. Detects a band of approximately 60 kDa (predicted molecular weight: 56 kDa).
ICC/IF Use at an assay dependent dilution. PubMed: 20335253

Target

  • FunctionModulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness.
  • Tissue specificityAdipocytes.
  • Sequence similaritiesBelongs to the perilipin family.
  • Post-translational
    modifications
    Major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis, by acting as a barrier in lipid droplet.
  • Cellular localizationLipid droplet. Lipid droplet surface-associated.
  • Information by UniProt
  • Database links
  • Alternative names
    • Lipid droplet associated protein antibody
    • Lipid droplet-associated protein antibody
    • PERI antibody
    • Perilipin antibody
    • Perilipin-1 antibody
    • PerilipinA antibody
    • PLIN antibody
    • PLIN1 antibody
    • PLIN1_HUMAN antibody
    see all

Anti-Perilipin A antibody images

References for Anti-Perilipin A antibody (ab60269)

This product has been referenced in:
  • Cheung W  et al. Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation and viral replication. J Virol 84:6782-98 (2010). ICC/IF ; Rhesus monkey . Read more (PubMed: 20335253) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab60269.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"