Anti-Peroxiredoxin 1 antibody [2A4] (ab16746)

Overview

  • Product nameAnti-Peroxiredoxin 1 antibody [2A4]
    See all Peroxiredoxin 1 primary antibodies
  • Description
    Mouse monoclonal [2A4] to Peroxiredoxin 1
  • Tested applicationsSuitable for: ELISA, IPmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Recombinant full length protein (Human).

  • Positive control
    • HeLa cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab16746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
IP
  • Application notesELISA: Use at an assay dependent dilution.
    IP: Use at a concentration of 1 - 2 µg/ml lysate.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInvolved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation.
    • Sequence similaritiesBelongs to the ahpC/TSA family.
      Contains 1 thioredoxin domain.
    • Post-translational
      modifications
      Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.
    • Cellular localizationCytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
    • Information by UniProt
    • Database links
    • Alternative names
      • Heme binding 23 kDa protein antibody
      • MSP23 antibody
      • Natural killer cell-enhancing factor A antibody
      • NKEF A antibody
      • NKEF-A antibody
      • NKEFA antibody
      • OSF3 antibody
      • Osteoblast specific factor 3 antibody
      • PAG antibody
      • Paga antibody
      • PAGB antibody
      • Peroxiredoxin-1 antibody
      • PRDX1 antibody
      • PRDX1_HUMAN antibody
      • Proliferation associated gene A antibody
      • Proliferation-associated gene protein antibody
      • PRX1 antibody
      • PrxI antibody
      • TDPX2 antibody
      • Thioredoxin peroxidase 2 antibody
      • Thioredoxin-dependent peroxide reductase 2 antibody
      see all

    References for Anti-Peroxiredoxin 1 antibody [2A4] (ab16746)

    ab16746 has not yet been referenced specifically in any publications.

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