Overview

  • Product nameAnti-Pescadillo antibody
    See all Pescadillo primary antibodies
  • Description
    Rabbit polyclonal to Pescadillo
  • Tested applicationsSuitable for: IHC-P, IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Dog, Pig, Xenopus laevis, Chimpanzee, Zebrafish, Rhesus monkey, Gorilla, Orangutan, Xenopus tropicalis
  • Immunogen

    Synthetic peptide corresponding to a region between residues 25 and 75 of human Pescadillo (NP_055118.1)

  • Positive control
    • HeLa whole cell lysate.

Properties

Associated products

Applications

Our Abpromise guarantee covers the use of ab72537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/5000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
IP Use at 2-5 µg/mg of lysate.
  • Application notesIs unsuitable for WB.
  • Target

    • FunctionComponent of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
    • Tissue specificitySignificant levels are detected in a variety of cancer cell lines, including glioblastoma, breast carcinoma, colon carcinoma and cervical carcinoma cells. Levels are abnormally elevated in malignant tumors of astrocytic origin.
    • Sequence similaritiesBelongs to the pescadillo family.
      Contains 1 BRCT domain.
    • Post-translational
      modifications
      Sumoylated.
    • Cellular localizationNucleus > nucleolus. Nucleus > nucleoplasm. Chromosome. Appears to localize to the periphery of metaphase chromosomes during mitosis and to the prenucleolar bodies that form in mitotic cells prior to the actual nucleoli.
    • Information by UniProt
    • Database links
    • Alternative names
      • FLJ43790 antibody
      • Homo sapiens pescadillo mRNA complete cds antibody
      • PES antibody
      • PES 1 antibody
      • pes1 antibody
      • PESC_HUMAN antibody
      • Pescadillo (zebrafish) homolog 1 containing BRCT domain antibody
      • Pescadillo homolog 1 antibody
      • Pescadillo homolog 1 containing BRCT domain (zebrafish) antibody
      • Pescadillo homolog antibody
      • Pescadillo ribosomal biogenesis factor 1 antibody
      see all

    Anti-Pescadillo antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma (left) and ovarian carcinoma (right) tissues labelling Pescadillo with ab72537 at 1/1000 (1 µg/ml). Detection: DAB.

    References for Anti-Pescadillo antibody (ab72537)

    ab72537 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"