The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 142 kDa.
FunctionRequired for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes.
Involvement in diseasePeroxisome biogenesis disorder complementation group 1 Peroxisome biogenesis disorder 1A Peroxisome biogenesis disorder 1B Heimler syndrome 1
Sequence similaritiesBelongs to the AAA ATPase family.
Cellular localizationCytoplasm. Peroxisome membrane. Associated with peroxisomal membranes.