• Product nameAnti-PEX14 antibody
    See all PEX14 primary antibodies
  • Description
    Rabbit polyclonal to PEX14
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthesized peptide derived from internal of Human PEX14.

  • Positive control
    • Human breast carcinoma tissue A549 cells



Our Abpromise guarantee covers the use of ab109999 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 41 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.


  • FunctionComponent of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
  • Involvement in diseaseDefects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791]. PBD-CGK is a peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
    Defects in PEX14 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.
  • Sequence similaritiesBelongs to the peroxin-14 family.
  • Cellular localizationPeroxisome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • dJ734G22.2 antibody
    • NAPP2 antibody
    • NF E2 associated polypeptide 2 antibody
    • Peroxin 14 antibody
    • Peroxin-14 antibody
    • Peroxisomal biogenesis factor 14 antibody
    • Peroxisomal membrane anchor protein PEX14 antibody
    • Peroxisomal membrane anchor protein Pex14p antibody
    • Peroxisomal membrane protein PEX14 antibody
    • pex14 antibody
    • PEX14_HUMAN antibody
    • Pex14p antibody
    • PTS1 receptor docking protein antibody
    • PTS1 receptor-docking protein antibody
    see all

Anti-PEX14 antibody images

  • Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using ab109999.
  • All lanes : Anti-PEX14 antibody (ab109999) at 1/500 dilution

    Lane 1 : A549 cells
    Lane 2 : A549 cells treated with the synthesized peptide

    Lysates/proteins at 5 µg per lane.

    Predicted band size : 41 kDa

References for Anti-PEX14 antibody (ab109999)

ab109999 has not yet been referenced specifically in any publications.

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