• Product name
  • Description
    Rabbit polyclonal to PEX14
  • Tested applications
    Suitable for: IPmore details
    Unsuitable for: WB
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 250-300 of Human PEX14 (NP_004556.1).

  • Positive control
    • HeLa whole cell lysate



Our Abpromise guarantee covers the use of ab113286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 2-5 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.
  • Target

    • Function
      Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17.
    • Involvement in disease
      Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791]. PBD-CGK is a peroxisomal disorder arising from a failure of protein import into the peroxisomal membrane or matrix. The peroxisome biogenesis disorders (PBD group) are genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies. Include disorders are: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum (PBD-ZSS).
      Defects in PEX14 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.
    • Sequence similarities
      Belongs to the peroxin-14 family.
    • Cellular localization
      Peroxisome membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • dJ734G22.2 antibody
      • NAPP2 antibody
      • NF E2 associated polypeptide 2 antibody
      • Peroxin 14 antibody
      • Peroxin-14 antibody
      • Peroxisomal biogenesis factor 14 antibody
      • Peroxisomal membrane anchor protein PEX14 antibody
      • Peroxisomal membrane anchor protein Pex14p antibody
      • Peroxisomal membrane protein PEX14 antibody
      • pex14 antibody
      • PEX14_HUMAN antibody
      • Pex14p antibody
      • PTS1 receptor docking protein antibody
      • PTS1 receptor-docking protein antibody
      see all

    Anti-PEX14 antibody images

    • Staining of PEX14 in HeLa whole cell lysate immunoprecipitated using ab113286 at 6 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane). Lane 2: controle IgG. Predicted band size : 41 kDa. Exposure time: 10 seconds.

    References for Anti-PEX14 antibody (ab113286)

    ab113286 has not yet been referenced specifically in any publications.

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