• Product nameAnti-PEX2 antibody
    See all PEX2 primary antibodies
  • Description
    Rabbit polyclonal to PEX2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the central region of Human PEX2 (NP_000309.1)

  • Positive control
    • Mouse cerebellum tissue lysates



Our Abpromise guarantee covers the use of ab95289 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 35 kDa.


  • FunctionSomewhat implicated in the biogenesis of peroxisomes.
  • Involvement in diseaseDefects in PEX2 are the cause of peroxisome biogenesis disorder complementation group 5 (PBD-CG5) [MIM:170993]; also known as PBD-CGF. PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). ZWS, NALD and IRD are distinct from RCDP and constitute a clinical continuum of overlapping phenotypes known as the Zellweger spectrum. The PBD group is genetically heterogeneous with at least 14 distinct genetic groups as concluded from complementation studies.
    Defects in PEX2 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.
    Defects in PEX2 are a cause of infantile Refsum disease (IRD) [MIM:266510]. IRD is a mild peroxisome biogenesis disorder (PBD). Clinical features include early onset, mental retardation, minor facial dysmorphism, retinopathy, sensorineural hearing deficit, hepatomegaly, osteoporosis, failure to thrive, and hypocholesterolemia. The biochemical abnormalities include accumulation of phytanic acid, very long chain fatty acids (VLCFA), di- and trihydroxycholestanoic acid and pipecolic acid.
  • Sequence similaritiesBelongs to the pex2/pex10/pex12 family.
    Contains 1 RING-type zinc finger.
  • Cellular localizationPeroxisome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 35 kDa peroxisomal membrane protein antibody
    • PAF-1 antibody
    • PAF1 antibody
    • Peroxin-2 antibody
    • peroxisomal biogenesis factor 2 antibody
    • Peroxisomal membrane protein 3 antibody
    • peroxisomal membrane protein 3, 35kDa antibody
    • Peroxisome assembly factor 1 antibody
    • Peroxisome biogenesis factor 2 antibody
    • PEX2 antibody
    • PEX2_HUMAN antibody
    • PMP3 antibody
    • PMP35 antibody
    • PXMP3 antibody
    • RING finger protein 72 antibody
    • RNF72 antibody
    • ZWS3 antibody
    see all

Anti-PEX2 antibody images

  • Anti-PEX2 antibody (ab95289) at 1/100 dilution + Mouse cerebellum tissue lysate at 35 µg

    Predicted band size : 35 kDa

References for Anti-PEX2 antibody (ab95289)

ab95289 has not yet been referenced specifically in any publications.

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