Overview

  • Product name
  • Description
    Rabbit polyclonal to PFTK1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to a region within amino acids 1-30 from the M1 region of Human PFTK1, conjugated to KLH.

  • Positive control
    • Mouse liver tissue lysates

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Purification notes
    ab104150 is purified through a protein A column, followed by peptide affinity purification.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab104150 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 53 kDa.

Target

  • Function
    Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.
  • Tissue specificity
    Highly expressed in brain, pancreas, kidney, heart, testis and ovary. Also detected at lower levels in other tissues except in spleen and thymus where expression is barely detected.
  • Sequence similarities
    Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
    Contains 1 protein kinase domain.
  • Cellular localization
    Cell membrane. Cytoplasm. Nucleus. Recruited to the cell membrane by CCNY.
  • Information by UniProt
  • Database links
  • Alternative names
    • cdk14 antibody
    • CDK14_HUMAN antibody
    • Cell division protein kinase 14 antibody
    • Cyclin-dependent kinase 14 antibody
    • hPFTAIRE1 antibody
    • KIAA0834 antibody
    • mKIAA0834 antibody
    • PFTAIRE protein kinase 1 antibody
    • PFTAIRE1 antibody
    • PFTK1 antibody
    • Serine/threonine protein kinase PFTAIRE 1 antibody
    • Serine/threonine-protein kinase PFTAIRE-1 antibody
    see all

Anti-PFTK1 antibody images

  • Anti-PFTK1 antibody (ab104150) at 1/100 dilution + Mouse liver tissue lysates at 35 µg

    Predicted band size : 53 kDa

References for Anti-PFTK1 antibody (ab104150)

This product has been referenced in:

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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