Overview

  • Product nameAnti-PGAM2 antibody
    See all PGAM2 primary antibodies
  • Description
    Rabbit polyclonal to PGAM2
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 19-49 of Human PGAM2 (NP_000281.2).

  • Positive control
    • NCI-H460 cell line lysate; Mouse testis tissue lysate

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Purification notesab107397 is purified through a protein A column, followed by peptide affinity purification.
  • ClonalityPolyclonal
  • IsotypeIgG

Applications

Our Abpromise guarantee covers the use of ab107397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 29 kDa.

Target

  • FunctionInterconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
  • Tissue specificityIn mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues.
  • Involvement in diseaseDefects in PGAM2 are the cause of glycogen storage disease type 10 (GSD10) [MIM:261670]. A metabolic disorder characterized by myoglobinuria, increased serum creatine kinase levels, decreased phosphoglycerate mutase activity, myalgia, muscle pain, muscle cramps and excercise intolerance.
  • Sequence similaritiesBelongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
  • Information by UniProt
  • Database links
  • Alternative names
    • BPG dependent PGAM 2 antibody
    • BPG-dependent PGAM 2 antibody
    • GSD10 antibody
    • MGC88743 antibody
    • Muscle specific phosphoglycerate mutase antibody
    • Muscle-specific phosphoglycerate mutase antibody
    • OTTHUMP00000207787 antibody
    • PGAM 2 antibody
    • PGAM M antibody
    • PGAM-M antibody
    • Pgam2 antibody
    • PGAM2_HUMAN antibody
    • PGAMM antibody
    • phosphoglycerate mutase 2 (muscle) antibody
    • Phosphoglycerate mutase 2 antibody
    • Phosphoglycerate mutase isozyme M antibody
    see all

Anti-PGAM2 antibody images

  • Anti-PGAM2 antibody (ab107397) at 1/100 dilution + NCI-H460 cell line lysate at 35 µg

    Predicted band size : 29 kDa
  • Anti-PGAM2 antibody (ab107397) at 1/100 dilution + Mouse testis tissue lysate at 35 µg

    Predicted band size : 29 kDa

References for Anti-PGAM2 antibody (ab107397)

ab107397 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"