Overview

  • Product nameAnti-PGEA1 antibody
    See all PGEA1 primary antibodies
  • Description
    Mouse monoclonal to PGEA1
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment, corresponding to amino acids 18-127 of Human PGEA1

Properties

Applications

Our Abpromise guarantee covers the use of ab57020 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionInhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
    • Tissue specificityWidely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.
    • Sequence similaritiesBelongs to the chibby family.
    • Cellular localizationNucleus speckle. Golgi apparatus, trans-Golgi network. Nuclear, in a punctate manner. Also found in the trans-Golgi.
    • Information by UniProt
    • Database links
    • Alternative names
      • ARPP-binding protein antibody
      • C22orf2 antibody
      • CBY antibody
      • Cby1 antibody
      • CBY1_HUMAN antibody
      • Cytosolic leucine rich protein antibody
      • Cytosolic leucine-rich protein antibody
      • Golgi and endoplasmic reticulum-associated 1 antibody
      • HRIHFB2025 antibody
      • PIGEA 14 antibody
      • PIGEA-14 antibody
      • PKD2 interactor antibody
      • PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 antibody
      • Protein Chibby antibody
      • Protein chibby homolog 1 antibody
      see all

    Anti-PGEA1 antibody images

    • Western blot against tagged recombinant protein immunogen using ab57020 PGEA1 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa

    References for Anti-PGEA1 antibody (ab57020)

    ab57020 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab57020.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"