Overview

  • Product name
  • Description
    Rabbit polyclonal to PGEA1
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    KLH conjugated synthetic peptide selected from the C terminal region of Human PGEA1 (NP_056188.1).

  • Positive control
    • MDA-MB231 cell line lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab95100 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 14 kDa.

Target

  • Function
    Inhibits the Wnt/Wingless pathway by binding to beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.
  • Tissue specificity
    Widely expressed. Expressed at higher levels in heart, skeletal muscle, kidney and placenta. Also found in brain, lung, liver and testis. Significantly down-regulated in thyroid and metastatic uterine tumors.
  • Sequence similarities
    Belongs to the chibby family.
  • Cellular localization
    Nucleus speckle. Golgi apparatus, trans-Golgi network. Nuclear, in a punctate manner. Also found in the trans-Golgi.
  • Information by UniProt
  • Database links
  • Alternative names
    • ARPP-binding protein antibody
    • C22orf2 antibody
    • CBY antibody
    • Cby1 antibody
    • CBY1_HUMAN antibody
    • Cytosolic leucine rich protein antibody
    • Cytosolic leucine-rich protein antibody
    • Golgi and endoplasmic reticulum-associated 1 antibody
    • HRIHFB2025 antibody
    • PIGEA 14 antibody
    • PIGEA-14 antibody
    • PKD2 interactor antibody
    • PKD2 interactor, Golgi and endoplasmic reticulum-associated 1 antibody
    • Protein Chibby antibody
    • Protein chibby homolog 1 antibody
    see all

Images

  • Anti-PGEA1 antibody (ab95100) at 1/100 dilution + MDA-MB231 cell line lysates at 35 µg

    Predicted band size : 14 kDa

References

ab95100 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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