Overview

  • Product name
    Anti-PGGT1B antibody
  • Description
    Rabbit polyclonal to PGGT1B
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    antigen sequence, corresponding to amino acids 213-347 of Human PGGT1B.

  • Positive control
    • Human breast tissue; RT 4, U 251 MG, Human liver and tonsil lysates.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer
    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity
    Immunogen affinity purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab122122 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/250 - 1/500.

Target

  • Function
    Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding.
  • Sequence similarities
    Belongs to the protein prenyltransferase subunit beta family.
    Contains 4 PFTB repeats.
  • Information by UniProt
  • Database links
  • Alternative names
    • BGGI antibody
    • Geranylgeranyl transferase type I subunit beta antibody
    • Geranylgeranyl transferase type-1 subunit beta antibody
    • Geranylgeranyltransferase type I beta subunit antibody
    • GGTase-I-beta antibody
    • GGTI antibody
    • PGGT1B antibody
    • PGTB1_HUMAN antibody
    • Protein geranylgeranyltransferase type I, beta subunit antibody
    • Type I protein geranyl-geranyltransferase subunit beta antibody
    see all

Images

  • Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells)
    Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells)
  • ab122122, at a 1/75 dilution, staining PGGT1B in paraffin-embedded Human breast tissue by Immunohistochemistry.
  • All lanes : Anti-PGGT1B antibody (ab122122) at 1/250 dilution

    Lane 1 : RT 4 lysate
    Lane 2 : U 251 MG lysate
    Lane 3 : Human plasma lysate
    Lane 4 : Human liver lysate
    Lane 5 : Human tonsil lysate

    Developed using the ECL technique.

References

ab122122 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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