Anti-PGRMC1 antibody - C-terminal (ab194963)

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Product name

Anti-PGRMC1 antibody - C-terminal
See all PGRMC1 primary antibodies
Description

Goat polyclonal to PGRMC1 - C-terminal
Host species

Goat
Tested applications

Suitable for: IHC-P, WBmore details
Species reactivity

Reacts with: Human
Predicted to work with: Rabbit, Horse, Cow, Pig, Monkey, Orangutan
Immunogen

Synthetic peptide corresponding to Human PGRMC1 aa 185-195 (C terminal) (Cysteine residue). (NP_006658.1)
Sequence:
EPKDESARKND

Database link: NP_006658.1

Run BLAST with Run BLAST with
Positive control
- Human testis tissue; Human liver lysate.

Form

Liquid
Storage instructions

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer

pH: 7.3
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline
Concentration information loading...
Purity

Immunogen affinity purified
Clonality

Polyclonal
Isotype

IgG
Research areas

Our Abpromise guarantee covers the use of ab194963 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application	Abreviews	Notes
IHC-P		Use a concentration of 5 µg/ml.
WB		Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 22 kDa.

Function

Receptor for progesterone.
Tissue specificity

Widely expressed, with highest expression in liver and kidney.
Sequence similarities

Belongs to the cytochrome b5 family. MAPR subfamily.
Contains 1 cytochrome b5 heme-binding domain.
Domain

The cytochrome b5 heme-binding domain lacks the conserved iron-binding His residues at positions 107 and 131.
Cellular localization

Microsome membrane. Endoplasmic reticulum membrane.
Target information above from: UniProt accession O00264 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Database links
- Entrez Gene: 317706 Cow
- Entrez Gene: 100058718 Horse
- Entrez Gene: 10857 Human
- Entrez Gene: 100174262 Orangutan
- Entrez Gene: 396946 Pig
- Entrez Gene: 100357097 Rabbit
- Omim: 300435 Human
- SwissProt: Q17QC0 Cow
- SwissProt: O00264 Human
- SwissProt: Q5RED0 Orangutan
- SwissProt: Q95250 Pig
- Unigene: 90061 Human
see all
Alternative names
- HPR6.6 antibody
- Membrane associated progesterone receptor component 1 antibody
- Membrane-associated progesterone receptor component 1 antibody
- mPR antibody
- PGRC1_HUMAN antibody
- PGRMC antibody
- Pgrmc1 antibody
- Progesterone binding protein antibody
- Progesterone receptor membrane component 1 antibody
see all

Western blot - Anti-PGRMC1 antibody - C-terminal (ab194963)

Anti-PGRMC1 antibody - C-terminal (ab194963) at 0.1 µg/ml + Human liver lysate (in RIPA buffer) at 35 µg

Developed using the ECL technique.

Predicted band size: 22 kDa

Primary incubation 1 hour.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PGRMC1 antibody - C-terminal (ab194963)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling PGRMC1 with ab194963 at 5 μg/ml.

ab194963 has not yet been referenced specifically in any publications.

Publishing research using ab194963? Please let us know so that we can cite the reference in this datasheet.

Customer reviews and Q&As

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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