Overview

  • Product name
    Anti-PGRP1B antibody [186C426]
    See all PGRP1B primary antibodies
  • Description
    Mouse monoclonal [186C426] to PGRP1B
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity

    Predicted to work with: Mouse, Rat, Human, Pig
  • Immunogen

    Synthetic peptide:

    CSQRLRELQAHHVHNN

    conjugated to KLH, corresponding to amino acids 95-110 of Human PGRP1B.

  • Positive control
    • Whole cell lysate from human brain.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.02% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • Purity
    Protein G purified
  • Clonality
    Monoclonal
  • Clone number
    186C426
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab13681 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2 µg/ml. Predicted molecular weight: 44.2 kDa.

Target

  • Function
    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • Tissue specificity
    Detected in skin epidermis, eccrine sweat glands and ducts, mucous cells in the submandibular salivary gland, mucous cells in the throat, ciliary body epithelial cells of the eye, small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). High expression in skin and esophagus. Expressed also to a much lesser extent in the tonsils and thymus.
  • Sequence similarities
    Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
  • Post-translational
    modifications
    N-glycosylated.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Peptidoglycan recognition protein 4 antibody
    • Peptidoglycan recognition protein I-beta antibody
    • Peptidoglycan recognition protein intermediate beta antibody
    • Pglyrp4 antibody
    • PGLYRPIbeta antibody
    • PGRP-I-beta antibody
    • PGRP4_HUMAN antibody
    • PGRPIB antibody
    • SBBI67 antibody
    see all

Images



  • Predicted band size : 44.2 kDa


    Western blot analysis of PGRP1B in cell lysates from human brain using ab13681 at a dilution of 2 µg/ml.

References

ab13681 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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