Overview

  • Product name
  • Description
    Goat polyclonal to PGRPS
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Dog
  • Immunogen

    Synthetic peptide:

    C-PGNQLYHLIQN

    , corresponding to C terminal amino acids 179-189 of human PGRPS (NP_005082.1).

  • Positive control
    • Jurkat cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab82163 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Predicted molecular weight: 22 kDa.
IHC-P Use a concentration of 3 - 6 µg/ml.

Target

  • Function
    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • Tissue specificity
    Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
  • Sequence similarities
    Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
  • Post-translational
    modifications
    N-glycosylated. N-glycosylation is required for bactericidal activity.
  • Cellular localization
    Secreted. Cytoplasmic granule.
  • Information by UniProt
  • Database links
  • Alternative names
    • MGC126894 antibody
    • MGC126896 antibody
    • Peptidoglycan recognition protein 1 antibody
    • Peptidoglycan recognition protein antibody
    • Peptidoglycan recognition protein short antibody
    • PGLYRP antibody
    • PGLYRP1 antibody
    • PGRP antibody
    • PGRP S antibody
    • PGRP-S antibody
    • PGRP1_HUMAN antibody
    • PHRP, short antibody
    • SBBI68 antibody
    • TAG7 antibody
    • TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein) antibody
    • TNFSF 3L antibody
    • TNFSF3L antibody
    • UNQ639/PRO1269 antibody
    see all

Anti-PGRPS antibody images

  • Anti-PGRPS antibody (ab82163) at 0.3 µg/ml + Jurkat cell lysate at 35 µg

    Predicted band size : 22 kDa
    Observed band size : 30 kDa (why is the actual band size different from the predicted?)
  • ab82163 at 3.8 µg/ml staining PGRPS in Human spleen by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

References for Anti-PGRPS antibody (ab82163)

ab82163 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab82163.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up