Acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
Acidic leucine-rich nuclear phosphoprotein 32 family member A
Acidic nuclear phosphoprotein pp32
Putative Human HLA Class II Associated Protein
RelevanceThis antibody recognizes all three identified isoforms of human, mouse and rat PHAP, including PHAP I, PHAP I2a, and PHAP III. The PHAP proteins(tumor suppressor putative HLA-DR associated proteins) are important regulators of mitochondrial apoptosis. PHAP facilitates apoptosome-mediated caspase-9 activation to stimulate the mitochondrial apoptosis pathway. In addition, PHAP opposes both Ras- and myc- mediated cell transformation.
References for PHAP peptide (ab6238)
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