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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer pH: 7.00 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 78.99% PBS, 1% BSA, 20% Glycerol
Concentration information loading...
Purity Immunogen affinity purified
Purification notes ab111844 is purified by antigen-affinity chromatography.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 35 kDa.
1/100 - 1/500.
Function May play a role in transcriptional regulation.
Tissue specificity Ubiquitously expressed.
Involvement in disease Defects in PHF6 are the cause of Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900]; also known as Boerjeson-Forssman syndrome (BORJ). BFLS is a X-linked recessive disorder characterized by moderate to severe mental retardation, epilepsy, hypogonadism, hypometabolism, obesity with marked gynecomastia, swelling of subcutaneous tissue of the face, narrow palpebral fissure and large but not deformed ears.
Sequence similarities Contains 2 PHD-type zinc fingers.
Post-translational modifications Phosphorylated upon DNA damage, probably by ATM or ATR.
Cellular localization Nucleus. Nucleus > nucleolus. Nuclear, it particularly localizes to the nucleolus.
Information by UniProt
Anti-PHD finger protein 6 antibody images
Western blot - PHD finger protein 6 antibody (ab111844)
Anti-PHD finger protein 6 antibody (ab111844) at 1/1000 dilution + MCF 7 whole cell lysate at 30 µg Predicted band size : 35 kDa
Immunocytochemistry/ Immunofluorescence - PHD finger protein 6 antibody (ab111844)
ab111844 at 1/500 dilution staining PHD finger protein 6 in Paraformaldehyde-fixed MCF7 cells by Immunofluorescence. Lower image shows cells co-stained with Hoechst 33342.
References for Anti-PHD finger protein 6 antibody (ab111844)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"