Anti-PHD finger protein 6 antibody (ab84537)

Overview

  • Product nameAnti-PHD finger protein 6 antibody
    See all PHD finger protein 6 primary antibodies
  • Description
    Rabbit polyclonal to PHD finger protein 6
  • Tested applicationsSuitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rabbit, Horse, Cow, Dog, Pig, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Chinese Hamster, Orangutan
  • Immunogen

    Synthetic peptide, corresponding to a region within residue 125 - 175 of Human PHD finger protein 6 (NP_115834.1)

  • Positive control
    • Human: anaplastic thyroid carcinoma, breast carcinoma, Hodgkin's lymphoma, ovarian carcinoma, prostate carcinoma. Mouse: renal cell carcinoma.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: 0.09% Sodium Azide
    Constituents: 0.1% BSA, Tris buffered saline
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityPolyclonal
  • IsotypeIgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84537 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
  • Application notesIHC-P: 1/100 - 1/500. Antigen retrieval with citrate buffer may enhance staining.
    Note: expected to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionMay play a role in transcriptional regulation.
    • Tissue specificityUbiquitously expressed.
    • Involvement in diseaseDefects in PHF6 are the cause of Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900]; also known as Boerjeson-Forssman syndrome (BORJ). BFLS is a X-linked recessive disorder characterized by moderate to severe mental retardation, epilepsy, hypogonadism, hypometabolism, obesity with marked gynecomastia, swelling of subcutaneous tissue of the face, narrow palpebral fissure and large but not deformed ears.
    • Sequence similaritiesContains 2 PHD-type zinc fingers.
    • Post-translational
      modifications
      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Cellular localizationNucleus. Nucleus > nucleolus. Nuclear, it particularly localizes to the nucleolus.
    • Information by UniProt
    • Database links
    • Alternative names
      • AC004383.6 antibody
      • BFLS antibody
      • BORJ antibody
      • CENP 31 antibody
      • Centromere protein 31 antibody
      • MGC14797 antibody
      • OTTHUMP00000024063 antibody
      • PHD finger protein 6 antibody
      • PHD like zinc finger protein antibody
      • PHD-like zinc finger protein antibody
      • Phf6 antibody
      • PHF6_HUMAN antibody
      see all

    Anti-PHD finger protein 6 antibody images

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human breast carcinoma, using 1/250 ab84537 followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Mouse renal cell carcinoma, using 1/250 ab84537 followed by DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Humanskin carcinoma, using 1/250 ab84537in conjunction with 1/100 Goat anti-Rabbit IgG conjugated with Hilyte PlusTM 555 (red).

    References for Anti-PHD finger protein 6 antibody (ab84537)

    ab84537 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab84537.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"