Rabbit monoclonal [EPR11996(B)] to PHD finger protein 6
WB, ICC/IFmore details Unsuitable for:
Flow Cyt,IHC-P or IP
Human Does not react with:
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PHD finger protein 6 aa 1-100 (Cysteine residue). The exact sequence is proprietary. Database link: Q8IWS0
K562, HeLa, Jurkat and 293T cell lysates, HeLa cells
This product is a recombinant rabbit monoclonal antibody.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Defects in PHF6 are the cause of Boerjeson-Forssman-Lehmann syndrome (BFLS) [MIM:301900]; also known as Boerjeson-Forssman syndrome (BORJ). BFLS is a X-linked recessive disorder characterized by moderate to severe mental retardation, epilepsy, hypogonadism, hypometabolism, obesity with marked gynecomastia, swelling of subcutaneous tissue of the face, narrow palpebral fissure and large but not deformed ears.
Contains 2 PHD-type zinc fingers.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Nucleus. Nucleus > nucleolus. Nuclear, it particularly localizes to the nucleolus.