Overview

  • Product name
  • Description
    Rabbit polyclonal to PHF17
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse
    Predicted to work with: Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 20-51 of Human PHF17 (NP_079176.2, NP_955352.1).

  • Positive control
    • Mouse heart tissue lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab116018 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 96 kDa.

Target

  • Function
    Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Transcriptional coactivator it may also promote acetylation of nucleosomal histone H4 by KAT5. Promotes apoptosis. May act as a renal tumor suppressor.
  • Tissue specificity
    Highly expressed in kidney. Also present in pancreas, liver and heart (at protein level). Down-regulated in renal cancer cells.
  • Sequence similarities
    Belongs to the JADE family.
    Contains 2 PHD-type zinc fingers.
  • Domain
    The 2 PHD-type zinc fingers are required for transcriptional activity.
  • Cellular localization
    Cytoplasm. Nucleus.
  • Information by UniProt
  • Database links
  • Alternative names
    • FLJ22479 antibody
    • Gene for apoptosis and differentiation in epithelia antibody
    • Jade family PHD finger 1 antibody
    • JADE1 antibody
    • JADE1_HUMAN antibody
    • KIAA1807 antibody
    • OTTHUMP00000219842 antibody
    • OTTHUMP00000219934 antibody
    • OTTHUMP00000219935 antibody
    • OTTHUMP00000219936 antibody
    • PHD finger protein 17 antibody
    • PHD protein Jade 1 antibody
    • Phf17 antibody
    • Protein Jade 1 antibody
    • Protein Jade-1 antibody
    see all

Images

  • Anti-PHF17 antibody (ab116018) at 1/100 dilution + Mouse heart tissue lysates at 35 µg

    Predicted band size : 96 kDa

References

ab116018 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab116018.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up