Overview

  • Product nameAnti-PHGDH antibody
    See all PHGDH primary antibodies
  • Description
    Mouse polyclonal to PHGDH
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length Human PHGDH protein, amino acids 1-533 (NP_006614.2)

  • Positive control
    • Raw 264.7, Jurkat and PHGDH transfected 293T cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab89073 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).

Target

  • PathwayAmino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 1/3.
  • Involvement in diseaseDefects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
  • Sequence similaritiesBelongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  • Information by UniProt
  • Database links
  • Alternative names
    • 3 PGDH antibody
    • 3-PGDH antibody
    • 3-phosphoglycerate dehydrogenase antibody
    • 3PGDH antibody
    • D-3-phosphoglycerate dehydrogenase antibody
    • EC 1.1.1.95 antibody
    • Epididymis secretory protein Li 113 antibody
    • HEL S 113 antibody
    • NLS antibody
    • NLS1 antibody
    • PDG antibody
    • PGAD antibody
    • PGD antibody
    • PGDH antibody
    • PGDH3 antibody
    • Phgdh antibody
    • PHGDHD antibody
    • Phosphoglycerate dehydrogenase antibody
    • SERA antibody
    • SERA_HUMAN antibody
    see all

Anti-PHGDH antibody images

  • Anti-PHGDH antibody (ab89073) at 1/500 dilution + Raw 264.7 cell lysate at 50 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • Anti-PHGDH antibody (ab89073) at 1/500 dilution + Jurkat cell lysate at 50 µg

    Predicted band size : 57 kDa
    Observed band size : 57 kDa
  • All lanes : Anti-PHGDH antibody (ab89073) at 1/500 dilution

    Lane 1 : PHGDH transfected 293T cell lysate
    Lane 2 : Non-transfected lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 57 kDa
    Observed band size : 57 kDa

References for Anti-PHGDH antibody (ab89073)

ab89073 has not yet been referenced specifically in any publications.

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