Anti-Phosphatidic acid phosphatase type 2B antibody [ZV002] (ab52581)

Overview

  • Product nameAnti-Phosphatidic acid phosphatase type 2B antibody [ZV002]
    See all Phosphatidic acid phosphatase type 2B primary antibodies
  • Description
    Mouse monoclonal [ZV002] to Phosphatidic acid phosphatase type 2B
  • SpecificityThis antibody is specific for the ~33-35 kDa human VCIP (vascular endothelial growth factor and type I collagen inducible protein, phosphatidic acid phosphatase 2b, PAP2b) protein.
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant protein derived from an internal region of human PPAP2b.

  • Positive control
    • Human PPAP2b-transfected 293 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab52581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 35 kDa.
ELISA Use a concentration of 0.1 - 1 µg/ml.

Target

  • FunctionCatalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1-phosphate (S-1-P). The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.
  • Tissue specificityUbiquitously expressed. Highly expressed in heart and placenta.
  • Sequence similaritiesBelongs to the PA-phosphatase related phosphoesterase family.
  • Post-translational
    modifications
    N-glycosylated. Contains high-mannose oligosaccharides.
  • Cellular localizationGolgi apparatus > trans-Golgi network membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Dri 42 antibody
    • Dri42 antibody
    • Lipid phosphate phosphohydrolase 3 antibody
    • LPP3 antibody
    • LPP3_HUMAN antibody
    • PAP 2b antibody
    • PAP-2b antibody
    • PAP2 beta antibody
    • PAP2-beta antibody
    • PAP2b antibody
    • Phosphatidate phosphohydrolase type 2b antibody
    • Phosphatidic acid phosphatase 2b antibody
    • Ppap2b antibody
    • type 2 phosphatidic acid phosphatase beta antibody
    • vascular endothelial growth factor and type I collagen inducible antibody
    • Vascular endothelial growth factor and type I collagen inducible protein antibody
    • Vascular endothelial growth factor and type I collagen-inducible protein antibody
    • VCIP antibody
    see all

References for Anti-Phosphatidic acid phosphatase type 2B antibody [ZV002] (ab52581)

ab52581 has not yet been referenced specifically in any publications.

Product Wall

I have just received a reply from the originator of the antibody, I hope this will also help you: "VCIP is also called PPAP2B: phosphatidic acid phosphatase type 2B. The protein encoded by this gene is a member of the phosphatidic acid phosphatase (...

Read More

Thank you for contacting us for technical support with ab52581. This antibody has so far not been tested in mouse samples though due to good homology of the immunogen with mouse PAP2B we would predict the antibody to cross react with the mouse prote...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"