Overview

  • Product name
    Anti-Phospholipase D1 antibody
    See all Phospholipase D1 primary antibodies
  • Description
    Rabbit polyclonal to Phospholipase D1
  • Specificity
    ab61125 detects endogenous levels of total Phospholipase D1 protein.
  • Tested applications
    Suitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human Phospholipase D1 around the phosphorylation site of serine 561.

  • Positive control
    • Human brain tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab61125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
IHC-P 1/50 - 1/100.

Target

  • Function
    Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
  • Tissue specificity
    Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
  • Sequence similarities
    Belongs to the phospholipase D family.
    Contains 1 PH domain.
    Contains 2 PLD phosphodiesterase domains.
    Contains 1 PX (phox homology) domain.
  • Cellular localization
    Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Choline phosphatase 1 antibody
    • hPLD1 antibody
    • Phosphatidylcholine-hydrolyzing phospholipase D1 antibody
    • Phospholipase D1 antibody
    • PLD 1 antibody
    • PLD1 antibody
    • PLD1_HUMAN antibody
    see all

Images

  • ab61125 at 1/50 dilution staining Phospholipase D1 in human brain by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.

References

ab61125 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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