Anti-Phospholipase D1 (phospho S561) antibody (ab60993)

Overview

  • Product nameAnti-Phospholipase D1 (phospho S561) antibody
    See all Phospholipase D1 primary antibodies
  • Description
    Rabbit polyclonal to Phospholipase D1 (phospho S561)
  • SpecificityDetects endogenous levels of Phospholipase D1 (PLD1) only when phosphorylated at serine 561.
  • Tested applicationsSuitable for: ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic phosphopeptide derived from human Phospholipase D1 around the phosphorylation site of serine 561 (K-F-SP-L-Y).

  • Positive control
    • Brain tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab60993 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/5000.
IHC-P 1/50 - 1/100.

Target

  • FunctionImplicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
  • Tissue specificityExpressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
  • Sequence similaritiesBelongs to the phospholipase D family.
    Contains 1 PH domain.
    Contains 2 PLD phosphodiesterase domains.
    Contains 1 PX (phox homology) domain.
  • Cellular localizationCytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Choline phosphatase 1 antibody
    • hPLD1 antibody
    • Phosphatidylcholine-hydrolyzing phospholipase D1 antibody
    • Phospholipase D1 antibody
    • PLD 1 antibody
    • PLD1 antibody
    • PLD1_HUMAN antibody
    see all

Anti-Phospholipase D1 (phospho S561) antibody images

  • Human brain tissue stained for Phospholipase D1 with ab60993 at 1/50-1/100 dilution, in the presence (right) or absence (left) of the immunizing phosphopeptide.

References for Anti-Phospholipase D1 (phospho S561) antibody (ab60993)

ab60993 has not yet been referenced specifically in any publications.

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