Anti-Phospholipase D1 (phospho T147) antibody (ab192801)

Overview

  • Product name
    Anti-Phospholipase D1 (phospho T147) antibody
    See all Phospholipase D1 primary antibodies
  • Description
    Rabbit polyclonal to Phospholipase D1 (phospho T147)
  • Host species
    Rabbit
  • Specificity
    ab192801 detects endogenous levels of Phospholipase D1 only when phosphorylated at Threonine 147.
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human Phospholipase D1 (phospho T147) conjugated to Keyhole Limpet Haemocyanin (KLH). Peptide sequence around phosphorylation site of threonine 147(R-H-T(p)-F-R).
    Database link: Q13393

  • Positive control
    • HepG2 cell extract.

Properties

Applications

Our Abpromise guarantee covers the use of ab192801 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 145 kDa.

Target

  • Function
    Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic.
  • Tissue specificity
    Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.
  • Sequence similarities
    Belongs to the phospholipase D family.
    Contains 1 PH domain.
    Contains 2 PLD phosphodiesterase domains.
    Contains 1 PX (phox homology) domain.
  • Cellular localization
    Cytoplasm > perinuclear region. Endoplasmic reticulum membrane. Golgi apparatus membrane. Late endosome membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Choline phosphatase 1 antibody
    • hPLD1 antibody
    • Phosphatidylcholine-hydrolyzing phospholipase D1 antibody
    • Phospholipase D1 antibody
    • PLD 1 antibody
    • PLD1 antibody
    • PLD1_HUMAN antibody
    see all

Images

  • All lanes : Anti-Phospholipase D1 (phospho T147) antibody (ab192801) at 1/500 dilution

    Lane 1 : HepG2 cell extract
    Lane 2 : HepG2 cell extract with antigen-specific peptide

    Predicted band size: 145 kDa

References

ab192801 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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