Overview

  • Product name
    Anti-Phosphorylase B antibody
    See all Phosphorylase B primary antibodies
  • Description
    Sheep polyclonal to Phosphorylase B
  • Specificity
    Recognizes Phosphorylase B. Exhibits high crossreactivity (95-135%) with Phosphorylase A by ELISA.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Rabbit
  • Immunogen

    Full length native protein: Phosphorylase B from rabbit muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab31121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/300 - 1/1000.
WB 1/500 - 1/1000. Predicted molecular weight: 121 kDa.

Target

  • Function
    Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
  • Pathway
    Glycan biosynthesis; glycogen metabolism.
  • Involvement in disease
    Glycogen storage disease 9B
  • Sequence similarities
    Belongs to the phosphorylase b kinase regulatory chain family.
  • Post-translational
    modifications
    Ser-701 is probably phosphorylated by PKA.
    Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Alternative names
    • DKFZp781E15103 antibody
    • FLJ41698 antibody
    • KPBB_HUMAN antibody
    • PHKB antibody
    • Phosphorylase b kinase regulatory subunit beta antibody
    • Phosphorylase kinase B antibody
    • Phosphorylase kinase beta polypeptide antibody
    • Phosphorylase kinase beta subunit antibody
    • Phosphorylase kinase subunit beta antibody
    see all

References

ab31121 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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