Overview

  • Product name
    Anti-Phosphorylase B antibody
    See all Phosphorylase B primary antibodies
  • Description
    Sheep polyclonal to Phosphorylase B
  • Specificity
    Recognizes Phosphorylase B. Exhibits high crossreactivity (95-135%) with Phosphorylase A by ELISA.
  • Tested applications
    Suitable for: ELISA, WBmore details
  • Species reactivity
    Reacts with: Rabbit
  • Immunogen

    Full length native protein: Phosphorylase B from rabbit muscle

Properties

Applications

Our Abpromise guarantee covers the use of ab31121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/300 - 1/1000.
WB 1/500 - 1/1000. Predicted molecular weight: 121 kDa.

Target

  • Function
    Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The beta chain acts as a regulatory unit and modulates the activity of the holoenzyme in response to phosphorylation.
  • Pathway
    Glycan biosynthesis; glycogen metabolism.
  • Involvement in disease
    Glycogen storage disease 9B
  • Sequence similarities
    Belongs to the phosphorylase b kinase regulatory chain family.
  • Post-translational
    modifications
    Ser-701 is probably phosphorylated by PKA.
    Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Alternative names
    • DKFZp781E15103 antibody
    • FLJ41698 antibody
    • KPBB_HUMAN antibody
    • PHKB antibody
    • Phosphorylase b kinase regulatory subunit beta antibody
    • Phosphorylase kinase B antibody
    • Phosphorylase kinase beta polypeptide antibody
    • Phosphorylase kinase beta subunit antibody
    • Phosphorylase kinase subunit beta antibody
    see all

References for Anti-Phosphorylase B antibody (ab31121)

ab31121 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab31121.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up