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Storage instructions Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage buffer Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7.0
Concentration information loading...
Purity Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 40 kDa.
1/100 - 1/200.
Function Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
Tissue specificity Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Pathway Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3. Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.
Involvement in disease Defects in PSAT1 are the cause of phosphoserine aminotransferase deficiency (PSATD) [MIM:610992]. PSATD is characterized biochemically by low plasma and cerebrospinal fluid concentrations of serine and glycine and clinically by intractable seizures, acquired microcephaly, hypertonia, and psychomotor retardation.
Sequence similarities Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
Information by UniProt
EC 188.8.131.52 antibody
Endometrial progesterone induced protein antibody
Anti-Phosphoserine Aminotransferase antibody images
Western blot - Phosphoserine Aminotransferase antibody (ab96136)
Anti-Phosphoserine Aminotransferase antibody (ab96136) at 1/1000 dilution + H1299 whole cell lysate at 30 µg Predicted band size : 40 kDa
Immunocytochemistry/ Immunofluorescence - Phosphoserine Aminotransferase antibody (ab96136)
ab96136, at 1/200 staining paraformaldehyde-fixed A549 cells by Immunofluorescence (Panel 1) and merged with DNA probe (Panel 2).
References for Anti-Phosphoserine Aminotransferase antibody (ab96136)
This product has been referenced in:
et al. Detailed Functional and Proteomic Characterization of Fludarabine Resistance in Mantle Cell Lymphoma Cells. PLoS One 10:e0135314 (2015).
Read more (PubMed: 26285204) »
et al. Differential expression of enzymes associated with serine/glycine metabolism in different breast cancer subtypes. PLoS One 9:e101004 (2014).
Read more (PubMed: 24979213) »
See all 2 Publications
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"